Several researchers have been working together and recently announced success in developing a drug that targets the symptoms of Alzheimer's disease in mice. They formed a drug called J147 that not only enhanced memory in normal mice but also prevented memory loss in mice with Alzheimer's. The research was published in the online journal PLoS ONE.
Until now, much research on drugs for Alzheimer's has focused on targeting one specific area, the amyloid beta peptide (Aß) which is the main component of the plaques affecting the brain in Alzheimer's. Noting, however, that most Alzheimer's is related to aging, J147 was designed to target several different causes of cognitive decline related to both Alzheimer's and normal aging.
Interestingly, J147's base is an Indian curry spice called Curcumin, which has been previously identified as a natural option to improve memory and even reduce pain. The researchers then added several other materials to the drug that promoted cell health.
Short term memory, long term memory, spatial memory, and working memory were all improved in normal mice who were given J147. Furthermore, when J147 was given to mice with Alzheimer's, they showed significant improvement in the ability to navigate a maze, while those who did not receive it showed no improvement.
Although it's not yet known if this will lead to success in treating humans, it's definitely another step in the right direction. I'll be watching for continued testing of J147 and pass on more information as I hear it.
On another note, check out these 6 tips to improve your memory and recall.