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Esther Heerema, MSW

TauRx Therapeutics to Trial Drug for Alzheimer's and Frontotemporal Dementia

By November 4, 2012

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According to the Alzheimer Research Forum, TauRx, a company based in Singapore, recently announced plans to conduct a phase three clinical trial for a drug called LMTX. LMTX is an updated version of a drug previously trialed called Rember that had been tested in 2008 with some positive results.

LMTX is slated to be tested on people with behavioral-variant frontotemporal dementia (bvFTD) with enrollment possibly beginning in November or December of this year. This type of frontotemporal dementia has historically been referred to as Pick's disease and affects between 50,000 to 60,000 Americans. The age of onset for bvFTD is generally younger than Alzheimer's and symptoms include behavioral and cognitive changes.

Two other phase three trials on LMTX are planned for testing in individuals with Alzheimer's, one targeting mild to moderate Alzheimer's lasting 12 months and one for those with mild Alzheimer's lasting 18 months.

More Information on Clinical Trials

Phase 3 Clinical Trial for bvFTD

Phase 3 Clinical Trial for Mild to Moderate AD

Phase 3 Clinical Trial for Mild AD

Alzheimer's Association Clinical TrialMatch Program

Have you or a loved one participated in a clinical trial? If so, feel free to comment on your experience or share your thoughts.

November 30, 2012 at 8:44 pm
(1) Sudha says:

My 88 year old mother participated in the clinical trial of rember (LTMX)in Singapore around 2006 or so. As care givers we are so grateful to TauX for allowing her to be part of this amazing drug. As a result of it, her quality of life has increased tremendously. Where prior to the drug she was depressed, listless, uninterested in things she used to enjoy, like reading, cooking, now she takes an active interest in the family, gardens, she can even manage reading books on a kindle. She basically lives a fairly normal and independent life. In fact recently she was activey following the American Presidential elections on CNN and the newspapers – she is Obama’s number 1 fan (:). Her short-term recall is so much better than it used to be.She is still forgetful of course, but that is to be expected given that she is 88 years old after all but it is certainly not to the extext that it was prior to the drug. Her quality of life is so much richer as a result of this drug and for that we are forever grateful. Thank you TauX. For those out there who are consideriing putting your loved ones on the drug, I would say – Go for it- you really have nothing to lose and everything to gain- there are no side effects – at least not for my mother. At the end of the day what we want for the people we loved who are faced with this dreaded disease, is to live a full life with dignity. We took that chance with the clinincal trial and all of us in my family are extremely thankful that my mother has that – an independent life that she lives with dignity.

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