The plaques and tangles so characteristic of Alzheimer's increase in different regions of the brain.

Alzheimer's About.com
Mild to Moderate Alzheimer's
Denial and a flattening of their mood becomes a feature. People with Alzheimer’s tend to back away from dealing with difficult or challenging situations.
The person with moderate Alzheimer's now cannot get by without assistance. They need help choosing proper attire. There is some disorientation in time, in interview they may be unable to recall important information of their current lives but can still remember major information about themselves, their family and others.
